An audit of performance, interpretation, and influence of pretherapeutic MRI in rectal cancer: a Swedish population-based cohort study.

Background The performance of magnetic resonance imaging (MRI) interpretation and communication of findings and its implication on treatment decisions has not fully been explored in rectal cancer. Purpose To investigate in a region the adherence to MRI protocol standards and the relation between MRI interpretation and selection to preoperative therapy in rectal cancer. Material and Methods Data on consecutive patients who underwent elective rectal cancer surgery in the region from January to June 2010 were obtained from the National Colorectal Cancer Registry.

Individual Reaction Mix 3

G065-3 200 reactions
EUR 167.00

3-D Life Thioglycerol

T10-3 180 µl
EUR 48.00

TGF-b-3 Transforming Growth Factor-Beta 3 Human Recombinant Protein, Plant

PROTP10600-3 Regular: 5ug
EUR 317.00
Description: TGFB3 Human Recombinant produced in plant is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 118 amino acids and having a molecular mass of 27.2kDa. ;The TGFB3 is fused to 6xHis tag at N-terminus and purified by standard chromatographic techniques.

Dr. P Kit-Solution 3

K2021010-3 50 ml
EUR 133.00
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Recombinant Human MMP-3 Protein

PROTP08254-3 10ug
EUR 317.00
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-3 degrades fibronectin, laminin, collagens III, IV, and X, and cartilage proteoglycans. Recombinant human MMP-3 is a 42.8 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (378 amino acids).

pLenti-CARM1 shRNA-3 Plasmid

PVTBAV03691-3 2 ug
EUR 356.00

pLenti-CTLA4 shRNA-3 Plasmid

PVTBAV05689-3 2 ug
EUR 356.00

pLenti-FOXM1 shRNA-3 Plasmid

PVTBAV08732-3 2 ug
EUR 356.00

pLenti-JUN shRNA-3 Plasmid

PVTBAV11741-3 2 ug
EUR 356.00

pLenti-LHX6 shRNA-3 Plasmid

PVTBAV12881-3 2 ug
EUR 356.00

pLenti-MAGEA3 shRNA-3 Plasmid

PVTBAV13661-3 2 ug
EUR 356.00

pLenti-RUNX3 shRNA-3 Plasmid

PVTBAV20583-3 2 ug
EUR 356.00

pLenti-Slc7a11 shRNA-3 Plasmid

PVTBAV21973-3 2 ug
EUR 356.00

pLenti-STAT3 shRNA-3 Plasmid

PVTBAV22921-3 2 ug
EUR 356.00

3-D Life PEG-Link

L50-3 3x 200 µl
EUR 94.00

3-D Life CD-Link

L60-3 3 x 200 µl
EUR 321.00

3-D-Life SG-PVA

M81-3 3x 170 µl
EUR 148.00

3-D Life FG-PVA

M82-3 3x 170 µl
EUR 148.00

3-D Life SG-Dextran

M91-3 3x 170 µl
EUR 157.00

3-D Life FG-Dextran

M92-3 3x 170 µl
EUR 157.00

3-D Life RGD Peptide

P10-3 3x 1 µmol
EUR 276.00

Anti-VEGF Receptor 3/FLT4 Antibody

A01276-3 100ug/vial
EUR 334.00

Caspase-3 Inhibitor Q-DEVD-OPh

1175-3
EUR 533.00

3-D Life Scrambled RGD Peptide

P11-3 3x 1 µmol
EUR 276.00

FSH (Human Follicle-stimulating hormone) ELISA test

3 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FSH (Human Follicle-stimulating hormone)

Anti-active Caspase-3 Rabbit Monoclonal Antibody

M00334-3 100ug/vial
EUR 397.00
Description: Anti-active Caspase-3 Rabbit Monoclonal Antibody tested for IF, IHC, ICC, WB in Human

Anti-Galectin 3/LGALS3 Antibody (monoclonal, 12B12)

M00621-3 100ug/vial
EUR 334.00

QuantiMir 3'-Universal Primer (10,000 qPCR reactions)

RA420AU-3 10,000 assays
EUR 178.00
  • Category: MicroRNA Tools

SeraMir 3'-Universal Primer (10,000 qPCR reactions)

RA800P-3 10,000 reactions
EUR 178.00
  • Category: MicroRNA Tools

Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit

30009-3 1KIT
EUR 809.00
Description: Minimum order quantity: 1 unit of 1KIT

Anti-Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Monoclonal Antibody

M00227-3 100ul
EUR 397.00
Description: Mouse Monoclonal Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Antibody. Validated in IHC, WB and tested in Equine.

3-D Life 10x CB-Buffer (pH 5.5)

B10-3 600 µl
EUR 44.00

3-D Life 10x CB Buffer (pH 7.2)

B20-3 600 µL
EUR 44.00

PLGF3 Human, Placenta Growth Factor-3 Human Recombinant Protein, sf9

PROTP49763-3 Regular: 25ug
EUR 317.00
Description: PLGF3 Human Recombinant produced in Spodoptera frugiperda is a glycosylated homodimer containing 2 chains of 203 amino acids (Leu19-Arg221) and having a molecular mass of 58kDa.;The PLGF-3 is purified by proprietary chromatographic techniques.

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)

M1030-3
EUR 441.00

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)

M1031-3
EUR 436.00

TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions)

M1032-3
EUR 436.00

TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions)

M1033-3
EUR 436.00

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions)

M1034-3
EUR 332.00

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions)

M1035-3
EUR 430.00

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions)

M1036-3
EUR 430.00

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions)

M1037-3
EUR 430.00

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 3 reactions)

M1039-3
EUR 436.00

ANGPTL3 (17-460)Human Angiopoietin-like Protein 3 (17-460 a.a.) Human Recombinant Protein

PROTQ9Y5C1-3 Regular: 10ug
EUR 317.00
Description: ANGPTL3 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 453 amino acids (17-460 a.a.) and having a molecular mass of 52.9kDa (Migrates at 25-70kDa on SDS-PAGE under reducing conditions). 

Lethal factor Protease Substrate 3, AMC derivative MEk2 peptide substrate for high-throughput screening of LF inhibitors (14aa)

LFPS-3 1 mg
EUR 408.00

Mouse Monoclonal anti-PEG (backbone specific) IgG (Clone #3)

PEG13-M-3 100 ug
EUR 482.00

Mouse Monoclonal anti-Clostridium difficile toxin A IgG (Clone #3)

CDTA12-M-3 100 ug
EUR 482.00

ABC diluent buffer

AR1106-3 12ml
EUR 91.00

Graduated Plastic Beakers, 100ml

BK044-3 1 UNIT
EUR 52.61
  • Product category: Labware/Beakers/100ml

Goat Gamma Globulin

22005-3 50g
EUR 1205.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Goat gamma globulin is purified from serum obtained from normal healthy animals (male and female) by using various fractionation procedures followed by dialysis against low ionic strength buffer. It is in lyophilized powder form with purity of 98% or more. Protein by weight: O.D. 280 nm E1%1.39: ? 85% - Residual salts, lipids, etc. comprise the rest of the weight.

Pig Serum, Non-Sterile, Trace-Hemolyzed

39519-3 500mL
EUR 149.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Whole blood is collected from healthy pigs of mixed breed, either sex and fasted at the time of slaughter. The blood is then refrigerated within 6 hours, processed within 24 hours and frozen at -20°C.

Bovine Serum Sterile, Non-Hemolyzed, Delipidized

37146-3 500mL
EUR 198.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Whole blood is collected from healthy animals of mixed breed both male and female that are 1+ years of age. The blood is refrigerated within 6 hours after collection and is processed within 24 hours and frozen at -20°C. The serum is then thawed in a cool water bath. First the lipids are removed, then the serum is filtered through a 0.22 micron filter. The obtained product is bottled and frozen at -20 ºC.

Horse Serum Non-Sterile, Non-Hemolyzed

39321-3 500mL
EUR 129.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Whole blood is collected from both male and female healthy horses living in a herd and are 1+ years of age. The blood is refrigerated within 6 hours after collection and is processed within 24 hours and frozen at -20°C.

Pig Serum, Non-Sterile, Trace-Hemolyzed

39328-3 3L
EUR 356.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Whole blood is collected from healthy pigs of mixed breed, either sex and fasted at the time of slaughter. The blood is then refrigerated within 6 hours, processed within 24 hours and frozen at -20°C.

Mouse anti-dsDNA IgG3-specific ELISA Kit, 96 tests, Quantitative

5120-3 1 kit
EUR 712.00

Anti-TNF alpha Antibody

A00002-3 100ug/vial
EUR 294.00

Anti-p16 Monoclonal Antibody

A00016-3 100ul
EUR 397.00
Description: Mouse Monoclonal Antibody for p16 Antibody (CDKN2A) detection. Tested with WB, IHC in Human, Mouse, Rat.

Anti-APP/C99 Antibody

A00081-3 100ug/vial
EUR 334.00

Anti-IL1 beta Antibody

A00101-3 100ug
EUR 455.00
Description: Rabbit Polyclonal IL1 beta Antibody. Validated in IP, IF, IHC, WB and tested in Mouse, Rat.

Anti-IL-6 Antibody

A00102-3 1mL
EUR 1232.00
Description: Rabbit Polyclonal IL-6 Antibody. Validated in IP, WB and tested in Human.

Anti-Nanog Antibody

A00153-3 100ug/vial
EUR 294.00

Anti-IL17C Antibody

A00164-3 100ug/vial
EUR 294.00

Anti-Flt3/CD135 Antibody

A00188-3 100ug/vial
EUR 334.00

Anti-Aryl hydrocarbon Receptor/Ahr Antibody

A00225-3 100ug/vial
EUR 294.00

Anti-CRP Antibody Fluorescein Conjugated

A00249-3 100ug
EUR 455.00
Description: Goat Polyclonal CRP Antibody Fluorescein Conjugated. Validated in WB and tested in Human.

Anti-BMAL1/ARNTL Antibody

A00260-3 100ug/vial
EUR 294.00

Anti-AICDA Antibody

A00267-3 100ug/vial
EUR 294.00

Anti-NFkB-p65 (Ab-276) Antibody

A00284-3 100ul
EUR 397.00
Description: Rabbit Polyclonal NFkB-p65 (Ab-276) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-ICOS Antibody

A00291-3 100ug/vial
EUR 334.00

Anti-TNF Receptor I/TNFRSF1A Antibody

A00294-3 100ug/vial
EUR 334.00

Anti-Interferon gamma/IFNG Antibody

A00393-3 100ug/vial
EUR 334.00

Anti-TLR1 Antibody

A00429-3 100ug/vial
EUR 334.00

Anti-IGFBP3 Antibody

A00435-3 100ug/vial
EUR 294.00

Anti-TANK Antibody

A00445-3 100ug/vial
EUR 334.00

Anti-beta 2 Microglobulin/B2m Antibody

A00456-3 100ug/vial
EUR 294.00

Anti-FGF23 Antibody

A00478-3 100ug/vial
EUR 294.00

Anti-Leptin Antibody

A00479-3 100ug/vial
EUR 294.00

Anti-CD5 Antibody

A00480-3 100ug/vial
EUR 334.00

Anti-SYK Antibody

A00490-3 100ug/vial
EUR 294.00

Anti-PON1 Antibody

A00516-3 100ug/vial
EUR 334.00

Anti-Cytochrome P450 17A1/Cyp17a1 Antibody

A00615-3 100ug/vial
EUR 334.00

Anti-CSF1 Antibody

A00620-3 100ug/vial
EUR 294.00

Anti-Polycystin 2/PKD2 Antibody

A00630-3 100ug/vial
EUR 334.00

Anti-IL1RA/Il1rn Antibody

A00651-3 100ug/vial
EUR 294.00

Anti-Smad1 (Ab-465) Antibody

A00728-3 100ul
EUR 397.00
Description: Rabbit Polyclonal Smad1 (Ab-465) Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-LOX 1/Olr1 Antibody

A00760-3 100ug/vial
EUR 334.00

Anti-Collagen III/COL3A1 Antibody

A00788-3 100ug/vial
EUR 334.00

Anti-LBP Antibody

A00809-3 100ug/vial
EUR 294.00

Anti-Fibrinogen alpha chain/FGA Antibody

A00816-3 100ug/vial
EUR 334.00

Anti-VEGF Receptor 2/Kdr Antibody

A00901-3 100ug/vial
EUR 334.00

Anti-Cystatin C/Cst3 Antibody

A00961-3 100ug/vial
EUR 294.00

Anti-IL22 Antibody

A00963-3 100ug/vial
EUR 294.00

Anti-uPA Receptor/PLAUR Antibody

A00993-3 100ug/vial
EUR 334.00

Anti-AMPK alpha 1/PRKAA1 Antibody

A00994-3 100ug/vial
EUR 294.00

Anti-MBL2 Antibody

A01000-3 100ug/vial
EUR 294.00

Anti-BCMA/Tnfrsf17 Antibody

A01014-3 100ug/vial
EUR 294.00

Anti-KCNH1 Antibody

A01036-3 100ug/vial
EUR 294.00

Anti-p90RSK (Ab-348) Antibody

A01058-3 100ul
EUR 397.00
Description: Rabbit Polyclonal p90RSK (Ab-348) Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-RANK/Tnfrsf11a Antibody

A01064-3 100ug/vial
EUR 294.00

Anti-CD40L/CD40LG Antibody

A01114-3 100ug/vial
EUR 294.00

Anti-PXR/NR1I2 Antibody

A01133-3 100ug/vial
EUR 334.00

Anti-IL12B Antibody

A01152-3 100ug/vial
EUR 334.00

Anti-Choline Acetyltransferase/CHAT Antibody

A01192-3 100ug/vial
EUR 334.00

Anti-TAPA1/Cd81 Antibody

A01281-3 100ug/vial
EUR 294.00

Anti-TrkB/NTRK2 Antibody

A01388-3 100ug/vial
EUR 294.00

Anti-PRMT1 Antibody

A01417-3 100ug/vial
EUR 294.00

Anti-CD31/Pecam1 Antibody

A01513-3 100ug/vial
EUR 334.00

Anti-Carbonic Anhydrase 4/CA4 Antibody

A01523-3 100ug/vial
EUR 334.00

Anti-Niemann Pick C2/NPC2 Antibody

A01582-3 100ug/vial
EUR 334.00

Anti-Nag-1 Antibody Peroxidase Conjugated

A01583-3 100ug
EUR 455.00
Description: Rabbit Polyclonal Nag-1 Antibody Peroxidase Conjugated. Validated in IHC, WB and tested in Human, Mouse.
Pretherapeutic MRI images were re-evaluated. Agreement between the original reports and the re-evaluation was compared using Cohen’s kappa coefficient. Results Among the 94 patients included, 81 (86%) had pretherapeutic MRI in accordance with defined imaging guidelines. In 34% of the original MR reports, data on extramural venous invasion (mrEMVI) and mrT category were not reported. Complete tumor staging was not possible because of missing data in 33 (35%) of the patients.
The agreement between the original MR reports and the re-evaluation regarding tumor stage was moderate (κ = 0.48). For decided treatment compared to recommended preoperative treatment according to the re-evaluation, the agreement was fair (κ = 0.33). Conclusion Established MRI protocol standards were not universally applied.
Missing data and inadequacies in original MRI reports resulted in moderate agreement between the original report and the re-evaluation indicating a risk of inappropriate treatment selection. The results call for further educational efforts in rectal cancer MRI acquisition and repeated audits of image protocol adherence and interpretation quality.