MK-5 with vented cover (polycarbonate

MK-5 with vented cover (polycarbonate

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MK-8745
B1942-5
EUR 153

MK-0752
B1980-5
EUR 457

MK-5172
B2118-5
EUR 185

MK-7655
B2289-5
EUR 196

MK-0557
B2317-5
EUR 196

MK-3903
B2431-5
EUR 414

MK-886
B2517-5
EUR 175

MK-0941
B1207-5
EUR 185

MK-8931
B1315-5
EUR 512

MK-5108
B1344-5
EUR 262

MK-1775
A5755-5 5 mg
EUR 148
Description: MK-1775 is a potent and selective Wee1 inhibitor with an IC50 of 5.2 nM in a cell-free assay. MK-1775 abolishes cyclin-dependent kinase 1 (CDC2) activity by phosphorylation of the Tyr15 residue [1].

MK-2461
A8476-5 5 mg
EUR 268
Description: MK-2461 is a potent inhibitor of Met, Flt1, Flt 3, Ron, PDGFR?, and Mer with IC50 of 2.5 nM, 10 nM, 22 nM, 7 nM, and 24 nM, respectively.

MK 6096
A8953-5 5 mg
EUR 321
Description: MK 6096

MK-4101
B7803-5 5 mg
EUR 261
Description: IC50: 1.5 ?mol/L for in mouse Light II cells by Gli_luc assayMK-4101 is a Hedgehog (Hh) signaling pathway inhibitor.Abnormal activation of the Hedgehog (Hh) signaling pathway is reported in the pathogenesis of various cancers, such as medulloblastoma and basal cell carcinoma.

MK 0893
A3608-5 5 mg
EUR 415
Description: MK 0893 is an inhibitor of both glucagon receptor and IGF-1R with IC50 values of 6.6nM and 6nM, respectively [1, 2].

MK-0591
A3609-5 5 mg
EUR 284
Description: MK-0591, an analog of MK-886 is a potent and orally active leukotriene biosynthesis inhibitor with an IC50 value of 600 ng/ml.

MK-0812
A3611-5 5 mg
EUR 379
Description: MK-0812 is an antagonist of chemokine receptor CCR-2 [1].C-C chemokine receptor type 2 (CCR-2) is a chemokine receptor expressing on monocytes and macrophages and plays a critical and apparently non-redundant role in orchestrating the trafficking of monocytes to tissues [1].

MK-0974
A3612-5 5 mg
EUR 395
Description: MK-0974 (Telcagepant) is a highly potent, selective, and orally bioavailable antagonist of CGRP receptor with IC50 value of 0.77 nM [1].

MK-2894
A3613-5 5 mg
EUR 357
Description: MK-2894 is a highly potent and selective inhibitor of EP4 receptor with IC50 value of 2.5 nM [1].

MK-3207
A3615-5 5 mg
EUR 340
Description: MK-3207 is a new, highly selective CGRP receptor antagonist that is approximately 40- to 65-fold more potent than telcagepant for the human CGRP receptor. The IC50 is 0.12 nM and The Ki value is 0.024 nM. It is highly selective versus human AM1, AM2, CTR, and AMY3.

MK-4827
A3617-5 5 mg
EUR 209
Description: MK-4827 is a novel, selective and orally bioavailable PARP1/PARP2 inhibitor with IC50 of 3.8 nM and 2.1 nM, respevctively.MK-4827 has shown great activity against cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1 [1].

MK-5172
A3618-5 5 mg
EUR 154
Description: MK-5172 is a selective inhibitor of Hepatitis C Virus NS3/4a Protease [1].Hepatitis C (HCV) virus is a member of the Flaviviridae family of viruses in the Hepacivirus genus and encoded by a 9.6-kb positive strand RNA genome [2].

MK-6892
A3623-5 5 mg
EUR 502
Description: Description:IC50 Value: 4.0 nM (Ki for Human GPR109A) [1]MK-6892 is a highly potential GPR109A agonists.in vitro: . Despite the increased serum shift of these compounds, the representative 1e was highly potent

MK-8033
A3624-5 5 mg
EUR 466
Description: MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing.

MK-0752
A4006-5 5 mg
EUR 247
Description: MK-0752 is a potent gamma secretase inhibitor in clinical development (IC50 ~50 nM).

MK-2048
A4072-5 5 mg
EUR 270
Description: MK-2048 is a second generation inhibitor of HIV-1 integrase with IC50 values of 0.075 ?M and 0.08 ?M for subtype B and subtype C integrase, respectively.Integration of viral cDNA into the host genome is one of the definitive features of retrovirus replication.

MK-8245
A4345-5 5 mg
EUR 268
Description: MK-8245 is a potent and liver-selective inhibitor of stearoyl-CoA desaturase (SCD) with IC50 value of 1nM [1].SCD1 represents a therapeutic target for the treatment of type II diabetes, dyslipidemia, obesity, and metabolic diseases.

MK 886
B6684-5 5 mg
EUR 137

MK 571
B7023-5 5 mg
EUR 128
Description: MK 571 (L-660,711) is a novel potent and selective antagonist of leukotriene D4 receptor with Ki values of 0.22 nM and 2.1 nM in guinea pig and human lung membranes, respectively [1].

Human Midkine (MK) ELISA Kit
DLR-MK-Hu-48T 48T
EUR 479
Description: A sandwich quantitative ELISA assay kit for detection of Human Midkine (MK) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Midkine (MK) ELISA Kit
DLR-MK-Hu-96T 96T
EUR 621
Description: A sandwich quantitative ELISA assay kit for detection of Human Midkine (MK) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Midkine (MK) ELISA Kit
DLR-MK-Mu-48T 48T
EUR 489
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Midkine (MK) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Midkine (MK) ELISA Kit
DLR-MK-Mu-96T 96T
EUR 635
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Midkine (MK) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Midkine (MK) ELISA Kit
DLR-MK-Ra-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rat Midkine (MK) in samples from serum, plasma or other biological fluids.

Rat Midkine (MK) ELISA Kit
DLR-MK-Ra-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rat Midkine (MK) in samples from serum, plasma or other biological fluids.

Human Midkine (MK) ELISA Kit
RD-MK-Hu-48Tests 48 Tests
EUR 478

Human Midkine (MK) ELISA Kit
RD-MK-Hu-96Tests 96 Tests
EUR 662

Mouse Midkine (MK) ELISA Kit
RD-MK-Mu-48Tests 48 Tests
EUR 489

Mouse Midkine (MK) ELISA Kit
RD-MK-Mu-96Tests 96 Tests
EUR 677

Rat Midkine (MK) ELISA Kit
RD-MK-Ra-48Tests 48 Tests
EUR 511

Rat Midkine (MK) ELISA Kit
RD-MK-Ra-96Tests 96 Tests
EUR 709

Human Midkine (MK) ELISA Kit
RDR-MK-Hu-48Tests 48 Tests
EUR 500

Human Midkine (MK) ELISA Kit
RDR-MK-Hu-96Tests 96 Tests
EUR 692

Mouse Midkine (MK) ELISA Kit
RDR-MK-Mu-48Tests 48 Tests
EUR 511

Mouse Midkine (MK) ELISA Kit
RDR-MK-Mu-96Tests 96 Tests
EUR 709

Rat Midkine (MK) ELISA Kit
RDR-MK-Ra-48Tests 48 Tests
EUR 534

Rat Midkine (MK) ELISA Kit
RDR-MK-Ra-96Tests 96 Tests
EUR 742

CORNING® 100X10MM PETRI DISH WITH COVER
70165-100 12/pk
EUR 105
Description: Vista Petri Dishes; PYREX VISTA Petri Dishes

CORNING® 100X15MM PETRI DISH WITH COVER
70165-101 12/pk
EUR 104
Description: Vista Petri Dishes; PYREX VISTA Petri Dishes

CORNING® 100X20MM PETRI DISH WITH COVER
70165-102 12/pk
EUR 104
Description: Vista Petri Dishes; PYREX VISTA Petri Dishes

MK-571 sodium
2692-5
EUR 185

MK-4827 (Tosylate)
B2003-5
EUR 240

Grazoprevir (MK-5172)
B2337-5
EUR 185

Odanacatib (MK-0822)
A2487-5 5 mg
EUR 166
Description: Odanacatib (MK-0822) is a potent, orally active and selective inhibitor of Cathepsin K with IC50 value of 0.20 nM [1],Cathepsin K is expressed predominantly in osteoclasts and degrades the collagen matrix componentsofbone.

MK-5172 hydrate
A3619-5 5 mg
EUR 212
Description: IC50 Value: 7.4nM and 7nM for genotype1b and 1a respectively, in replicon system [1]MK-5172 is a novel P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.

Raltegravir (MK-0518)
A4073-5 5 mg
EUR 148
Description: Raltegravir, formerly named MK-0518, is an HIV-1 integrase strand transfer inhibitor which has been shown to have activity against multidrug-resistant HIV-1 and both CCR5-trophic and CXCR4-trophic HIV-1 in vitro.

Anacetrapib (MK-0859)
A4375-5 5 mg
EUR 189
Description: Anacetrapib, also known as MK-0859, is a potent and selective inhibitor of cholesteryl ester transfer protein (CETP) that exhibits strong inhibition against CETP-mediated transfer of cholesteryl esters and triglycerides with values of inhibition constant IC50 of 16 nM and 29 nM respectively.

MK-4827 Racemate
B3393-5 5 mg
EUR 209
Description: MK-4827 racemate (Niraparib racemate) is a selective inhibitor of PARP1/2 with IC50 of 3.8 nM/2.1 nM; >330-fold selective against PARP3, V-PARP and Tank1.

MK-4827 hydrochloride
B1163-5 5 mg
EUR 212
Description: MK-4827(Niraparib) Hcl is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.

MK-4827 tosylate
B1164-5 5 mg
EUR 232
Description: MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.

MK-3207 HCl
B1436-5 5 mg
EUR 303
Description: MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3.

Verubecestat (MK-8931)
B6195-5 5 mg
EUR 160
Description: Ki: 2.2 and 3.4 nM for human and mouse Bace1, respectivelyVerubecestat (MK-8931) is a BACE1 inhibitor.?-Amyloid (A?) peptides are regarded to be involved in the etiology of AD.

Cover Plate
1292235 5unit
EUR 251

CORNING®150X20 MM PETRI DISH WITH COVER
70165-152 12/pk
EUR 243
Description: Vista Petri Dishes; PYREX VISTA Petri Dishes

(+)-MK 801 Hydrogen Maleate
B2326-5
EUR 131

(-)-MK 801 Hydrogen Maleate
B2327-5
EUR 131

MK-591 sodium salt
B2519-5
EUR 349

MK-591, Free acid
B2520-5
EUR 349

MK-8776 (SCH-900776)
A8477-5 5 mg
EUR 177
Description: SCH 900776 is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1), Chk2 and Cdk3 with IC50 value of 3 nM, 1.5µM and 0.16 µM, respectively.

MK-5172 potassium salt
A3620-5 5 mg
EUR 212
Description: IC50 Value: 7.4nM and 7nM for genotype1b and 1a respectively, in replicon system [1]MK-5172 is a novel P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.

MK-5172 sodium salt
A3621-5 5 mg
EUR 212
Description: IC50 Value: 7.4nM and 7nM for genotype1b and 1a respectively, in replicon system [1]MK-5172 is a novel P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.

MK-5108 (VX-689)
A4120-5 5 mg
EUR 189
Description: MK-5108, also known as VX-689, is a novel, potent and selective inhibitor of Aurora A kinase (AAK) that competitively binds to the ATP binding site of AAK and hence potently inhibits the activity of AAK with 50% inhibition concentration IC50 value of 0.064 nM

Stainless Steel Dish with Cover (for 30 Slide Holder)
IMS004 1 ea.
EUR 96

MK-571 sodium salt hydrate
B8031-5 5 mg
EUR 115
Description: MK571 sodium salt is a specific CysLT1 (Cysteinyl-Leukotriene Type 1 Receptor) antagonist [1].Cysteinyl leukotriene receptor 1, also termed as CYSLTR1, is a receptor for cysteinyl leukotrienes (LT)which mediates a large variety of allergic and hypersensitivity reactions in humans [2].

Orange viewing cover
E5001-OC 1 PC
EUR 87.62

FALCON® 875CM² RECTANGULAR STRAIGHT NECK CELL CULTURE MULTI-FLASK, 5-LAYER WITH VENTED CAP
353144 8/pk
EUR 167
Description: Lab Cell Culture - DL; High Density Flasks

BATTERY COVER WITH WINGS FOR CORNING® STRIPETTOR™ ULTRA
4995 3/pk
EUR 44
Description: Handheld Pipettor Repairs; Liquid Handling Device Repairs

CORNING®60 X 15 MM PETRI DISH WITH COVER
70165-60 12/pk
EUR 119
Description: Vista Petri Dishes; PYREX VISTA Petri Dishes

TubeRoller with 5 rollers
R3005-E 1 PC
EUR 1065.86
Description: TubeRoller ensures gentle rolling motion, Smooth +/-5° tilt action, available for tubes/bottles from 8mm to 200mm diameter

FALCON® 25CM² RECTANGULAR CANTED NECK CELL CULTURE FLASK WITH VENTED CAP
353108 20/pk
EUR 82
Description: Lab Cell Culture - DL; TC Flasks - DL

FALCON® 25CM² RECTANGULAR CANTED NECK CELL CULTURE FLASK WITH VENTED CAP
353109 20/pk
EUR 85
Description: Lab Cell Culture - DL; TC Flasks - DL

FALCON® 75CM² RECTANGULAR STRAIGHT NECK CELL CULTURE FLASK WITH VENTED CAP
353110 5/pk
EUR 118
Description: Lab Cell Culture - DL; TC Flasks - DL

FALCON® 175CM² RECTANGULAR STRAIGHT NECK CELL CULTURE FLASK WITH VENTED CAP
353112 5/pk
EUR 101
Description: Lab Cell Culture - DL; TC Flasks - DL

FALCON® 75CM² RECTANGULAR CANTED NECK CELL CULTURE FLASK WITH VENTED CAP
353136 5/pk
EUR 83
Description: Lab Cell Culture - DL; TC Flasks - DL

FALCON® 225CM² RECTANGULAR CANTED NECK CELL CULTURE FLASK WITH VENTED CAP
353138 5/pk
EUR 139
Description: Lab Cell Culture - DL; TC Flasks - DL

FALCON® 150CM² RECTANGULAR CANTED NECK CELL CULTURE FLASK WITH VENTED CAP
355001 5/pk
EUR 112
Description: Lab Cell Culture - DL; TC Flasks - DL

CORNING® BIOCOAT™ POLY-D-LYSINE 175CM² FLASK WITH VENTED CAP
356539 5/pk
EUR 552
Description: Advanced Cells - DL; Flasks BCT

MK-3102
9599-1
EUR 153

MK-4827
9462-25
EUR 1023

MK-1775
2373-25
EUR 430

MK-571
2691-25
EUR 544

MK-2206
1888-1000
EUR 240

MK-2206
1888-500
EUR 156

MK-1064
B1641-25
EUR 865

MK-8745
B1942-25
EUR 457

MK-0752
B1980-1
EUR 153

MK-5172
B2118-25
EUR 588

MK-7655
B2289-25
EUR 631

MK-0557
B2317-25
EUR 631

MK-3903
B2431-1
EUR 142

MK-886
B2517-25
EUR 544

MK-0941
B1207-25
EUR 588

MK-8931
B1315-1
EUR 175

MK-5108
B1344-25
EUR 756

MK-677
abx188791-10g 10 g
EUR 606

Mk-0822
20-abx182578
  • EUR 1455.00
  • EUR 620.00
  • 100 mg
  • 10 mg

Mk-2206
20-abx182579
  • EUR 1024.00
  • EUR 2527.00
  • 100 mg
  • 1 g

MK-8745
HY-13819 10mM/1mL
EUR 141

MK-886
HY-14166 5mg
EUR 147

MK-5046
HY-14342 100mg
EUR 2736

MK-0429
HY-15102 100mg
EUR 3896

MK-0557
HY-15411 10mM/1mL
EUR 263

MK-7622
HY-15618 5mg
EUR 176

MK-7246
HY-15853 50mg
EUR 2116

MK-1064
HY-19914 100mg
EUR 1413

MK 0893
HY-50663 10mM/1mL
EUR 611

MK-0812
HY-50669 5mg
EUR 257

MK-2461
HY-50703 50mg
EUR 1703

MK-2894
HY-10413 50mg
EUR 1538

MK-6892
HY-10680 100mg
EUR 1978

MK-4074
HY-107709 10mM/1mL
EUR 407

MK-3903
HY-107988 10mM/1mL
EUR 429

MK-0752
HY-10974 100mg
EUR 1466

MK-0773
HY-11027 100mg
EUR 1978

MK-8353
HY-111407 1mg
EUR 113

MK-3697
HY-12301 50mg
EUR 1076

MK-0354
HY-13008 10mM/1mL
EUR 277

MK-8245
HY-13070 10mM/1mL
EUR 191

MK-5108
HY-13252 100mg
EUR 1083

MK-8033
HY-13299 5mg
EUR 573

MK-2048
HY-13305 1mg
EUR 257

MK-4256
HY-13466 100mg
EUR 4596

MK-4101
HY-100036 100mg
EUR 854

MK-3328
HY-100275 1mg
EUR 912

MK-447
HY-100297 10mg
EUR 1706

MK-6913
HY-100327 10mg
EUR 6122

MK-8617
HY-101023 50mg
EUR 567

MK-8998
HY-101096 100mg
EUR 2943

MK-6240
HY-101186 50mg
EUR 3206

MK-3207
HY-10301 5mg
EUR 271

MK-0249
HY-U00076 5mg
EUR 2288

MK-0752
E1KS2660 5mg
EUR 1111

MK-2206
E1KS1078 5 mg
EUR 443

MK 3207
E1KS1542 10mg
EUR 1504

MK-1775
A5755-10 10 mg
EUR 200
Description: MK-1775 is a potent and selective Wee1 inhibitor with an IC50 of 5.2 nM in a cell-free assay. MK-1775 abolishes cyclin-dependent kinase 1 (CDC2) activity by phosphorylation of the Tyr15 residue [1].

MK-1775
A5755-100 100 mg
EUR 815
Description: MK-1775 is a potent and selective Wee1 inhibitor with an IC50 of 5.2 nM in a cell-free assay. MK-1775 abolishes cyclin-dependent kinase 1 (CDC2) activity by phosphorylation of the Tyr15 residue [1].

MK-1775
A5755-5.1 10 mM (in 1mL DMSO)
EUR 166
Description: MK-1775 is a potent and selective Wee1 inhibitor with an IC50 of 5.2 nM in a cell-free assay. MK-1775 abolishes cyclin-dependent kinase 1 (CDC2) activity by phosphorylation of the Tyr15 residue [1].

MK-1775
A5755-50 50 mg
EUR 508
Description: MK-1775 is a potent and selective Wee1 inhibitor with an IC50 of 5.2 nM in a cell-free assay. MK-1775 abolishes cyclin-dependent kinase 1 (CDC2) activity by phosphorylation of the Tyr15 residue [1].

MK-1775
A5755-S Evaluation Sample
EUR 81
Description: MK-1775 is a potent and selective Wee1 inhibitor with an IC50 of 5.2 nM in a cell-free assay. MK-1775 abolishes cyclin-dependent kinase 1 (CDC2) activity by phosphorylation of the Tyr15 residue [1].

MK-2461
A8476-10 10 mg
EUR 432
Description: MK-2461 is a potent inhibitor of Met, Flt1, Flt 3, Ron, PDGFR?, and Mer with IC50 of 2.5 nM, 10 nM, 22 nM, 7 nM, and 24 nM, respectively.

MK-2461
A8476-5.1 10 mM (in 1mL DMSO)
EUR 287
Description: MK-2461 is a potent inhibitor of Met, Flt1, Flt 3, Ron, PDGFR?, and Mer with IC50 of 2.5 nM, 10 nM, 22 nM, 7 nM, and 24 nM, respectively.

(+)-MK 801
A3100-10 10 mg
EUR 105
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.

(+)-MK 801
A3100-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.

(+)-MK 801
A3100-50 50 mg
EUR 266
Description: (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM [1].MK 801 is a potent anticonvulsant exhibits both anxiolytic and sympathomimetic properties.

MK-8745
A8807-10 10 mg
EUR 128
Description: MK-8745 is a novel and selective inhibitor of Aurora A with IC50 value of 0.6 nM [1].Aurora A kinase is a member of mitotic serine/threonine kinases and plays an important role in cellular division by controlling chromatid segregation.

MK-8745
A8807-5.1 10 mM (in 1mL DMSO)
EUR 119
Description: MK-8745 is a novel and selective inhibitor of Aurora A with IC50 value of 0.6 nM [1].Aurora A kinase is a member of mitotic serine/threonine kinases and plays an important role in cellular division by controlling chromatid segregation.

MK-8745
A8807-50 50 mg
EUR 268
Description: MK-8745 is a novel and selective inhibitor of Aurora A with IC50 value of 0.6 nM [1].Aurora A kinase is a member of mitotic serine/threonine kinases and plays an important role in cellular division by controlling chromatid segregation.

MK 6096
A8953-10 10 mg
EUR 502
Description: MK 6096

MK 6096
A8953-100 100 mg
EUR 1823
Description: MK 6096

MK 6096
A8953-5.1 10 mM (in 1mL DMSO)
EUR 348
Description: MK 6096

MK 6096
A8953-50 50 mg
EUR 1225
Description: MK 6096

MK-4101
B7803-10 10 mg
EUR 366
Description: IC50: 1.5 ?mol/L for in mouse Light II cells by Gli_luc assayMK-4101 is a Hedgehog (Hh) signaling pathway inhibitor.Abnormal activation of the Hedgehog (Hh) signaling pathway is reported in the pathogenesis of various cancers, such as medulloblastoma and basal cell carcinoma.

MK-4101
B7803-100 100 mg
EUR 2312
Description: IC50: 1.5 ?mol/L for in mouse Light II cells by Gli_luc assayMK-4101 is a Hedgehog (Hh) signaling pathway inhibitor.Abnormal activation of the Hedgehog (Hh) signaling pathway is reported in the pathogenesis of various cancers, such as medulloblastoma and basal cell carcinoma.

MK-4101
B7803-5.1 10 mM (in 1mL DMSO)
EUR 279
Description: IC50: 1.5 ?mol/L for in mouse Light II cells by Gli_luc assayMK-4101 is a Hedgehog (Hh) signaling pathway inhibitor.Abnormal activation of the Hedgehog (Hh) signaling pathway is reported in the pathogenesis of various cancers, such as medulloblastoma and basal cell carcinoma.

MK-4101
B7803-50 50 mg
EUR 1286
Description: IC50: 1.5 ?mol/L for in mouse Light II cells by Gli_luc assayMK-4101 is a Hedgehog (Hh) signaling pathway inhibitor.Abnormal activation of the Hedgehog (Hh) signaling pathway is reported in the pathogenesis of various cancers, such as medulloblastoma and basal cell carcinoma.

MK 0893
A3608-10 10 mg
EUR 711
Description: MK 0893 is an inhibitor of both glucagon receptor and IGF-1R with IC50 values of 6.6nM and 6nM, respectively [1, 2].

MK 0893
A3608-5.1 10 mM (in 1mL DMSO)
EUR 525
Description: MK 0893 is an inhibitor of both glucagon receptor and IGF-1R with IC50 values of 6.6nM and 6nM, respectively [1, 2].

MK 0893
A3608-50 50 mg
EUR 1703
Description: MK 0893 is an inhibitor of both glucagon receptor and IGF-1R with IC50 values of 6.6nM and 6nM, respectively [1, 2].

MK-0591
A3609-10 10 mg
EUR 366
Description: MK-0591, an analog of MK-886 is a potent and orally active leukotriene biosynthesis inhibitor with an IC50 value of 600 ng/ml.

MK-0591
A3609-100 100 mg
EUR 2222
Description: MK-0591, an analog of MK-886 is a potent and orally active leukotriene biosynthesis inhibitor with an IC50 value of 600 ng/ml.

MK-0591
A3609-5.1 10 mM (in 1mL DMSO)
EUR 354
Description: MK-0591, an analog of MK-886 is a potent and orally active leukotriene biosynthesis inhibitor with an IC50 value of 600 ng/ml.

MK-0591
A3609-50 50 mg
EUR 1453
Description: MK-0591, an analog of MK-886 is a potent and orally active leukotriene biosynthesis inhibitor with an IC50 value of 600 ng/ml.

MK-0812
A3611-1 1 mg
EUR 132
Description: MK-0812 is an antagonist of chemokine receptor CCR-2 [1].C-C chemokine receptor type 2 (CCR-2) is a chemokine receptor expressing on monocytes and macrophages and plays a critical and apparently non-redundant role in orchestrating the trafficking of monocytes to tissues [1].

MK-0812
A3611-10 10 mg
EUR 666
Description: MK-0812 is an antagonist of chemokine receptor CCR-2 [1].C-C chemokine receptor type 2 (CCR-2) is a chemokine receptor expressing on monocytes and macrophages and plays a critical and apparently non-redundant role in orchestrating the trafficking of monocytes to tissues [1].

MK-0974
A3612-1 1 mg
EUR 126
Description: MK-0974 (Telcagepant) is a highly potent, selective, and orally bioavailable antagonist of CGRP receptor with IC50 value of 0.77 nM [1].

MK-0974
A3612-10 10 mg
EUR 661
Description: MK-0974 (Telcagepant) is a highly potent, selective, and orally bioavailable antagonist of CGRP receptor with IC50 value of 0.77 nM [1].

MK-2894
A3613-10 10 mg
EUR 567
Description: MK-2894 is a highly potent and selective inhibitor of EP4 receptor with IC50 value of 2.5 nM [1].

MK-2894
A3613-50 50 mg
EUR 2004
Description: MK-2894 is a highly potent and selective inhibitor of EP4 receptor with IC50 value of 2.5 nM [1].

MK-3207
A3615-10 10 mg
EUR 547
Description: MK-3207 is a new, highly selective CGRP receptor antagonist that is approximately 40- to 65-fold more potent than telcagepant for the human CGRP receptor. The IC50 is 0.12 nM and The Ki value is 0.024 nM. It is highly selective versus human AM1, AM2, CTR, and AMY3.

MK-4827
A3617-10 10 mg
EUR 318
Description: MK-4827 is a novel, selective and orally bioavailable PARP1/PARP2 inhibitor with IC50 of 3.8 nM and 2.1 nM, respevctively.MK-4827 has shown great activity against cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1 [1].

MK-4827
A3617-100 100 mg
EUR 1636
Description: MK-4827 is a novel, selective and orally bioavailable PARP1/PARP2 inhibitor with IC50 of 3.8 nM and 2.1 nM, respevctively.MK-4827 has shown great activity against cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1 [1].

MK-4827
A3617-50 50 mg
EUR 951
Description: MK-4827 is a novel, selective and orally bioavailable PARP1/PARP2 inhibitor with IC50 of 3.8 nM and 2.1 nM, respevctively.MK-4827 has shown great activity against cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1 [1].

MK-5172
A3618-10 10 mg
EUR 212
Description: MK-5172 is a selective inhibitor of Hepatitis C Virus NS3/4a Protease [1].Hepatitis C (HCV) virus is a member of the Flaviviridae family of viruses in the Hepacivirus genus and encoded by a 9.6-kb positive strand RNA genome [2].

MK-5172
A3618-100 100 mg
EUR 804
Description: MK-5172 is a selective inhibitor of Hepatitis C Virus NS3/4a Protease [1].Hepatitis C (HCV) virus is a member of the Flaviviridae family of viruses in the Hepacivirus genus and encoded by a 9.6-kb positive strand RNA genome [2].

MK-5172
A3618-5.1 10 mM (in 1mL DMSO)
EUR 186
Description: MK-5172 is a selective inhibitor of Hepatitis C Virus NS3/4a Protease [1].Hepatitis C (HCV) virus is a member of the Flaviviridae family of viruses in the Hepacivirus genus and encoded by a 9.6-kb positive strand RNA genome [2].

MK-5172
A3618-50 50 mg
EUR 572
Description: MK-5172 is a selective inhibitor of Hepatitis C Virus NS3/4a Protease [1].Hepatitis C (HCV) virus is a member of the Flaviviridae family of viruses in the Hepacivirus genus and encoded by a 9.6-kb positive strand RNA genome [2].

MK-6892
A3623-10 10 mg
EUR 737
Description: Description:IC50 Value: 4.0 nM (Ki for Human GPR109A) [1]MK-6892 is a highly potential GPR109A agonists.in vitro: . Despite the increased serum shift of these compounds, the representative 1e was highly potent

MK-6892
A3623-100 100 mg
EUR 2583
Description: Description:IC50 Value: 4.0 nM (Ki for Human GPR109A) [1]MK-6892 is a highly potential GPR109A agonists.in vitro: . Despite the increased serum shift of these compounds, the representative 1e was highly potent

MK-6892
A3623-5.1 10 mM (in 1mL DMSO)
EUR 547
Description: Description:IC50 Value: 4.0 nM (Ki for Human GPR109A) [1]MK-6892 is a highly potential GPR109A agonists.in vitro: . Despite the increased serum shift of these compounds, the representative 1e was highly potent

MK-6892
A3623-50 50 mg
EUR 1678
Description: Description:IC50 Value: 4.0 nM (Ki for Human GPR109A) [1]MK-6892 is a highly potential GPR109A agonists.in vitro: . Despite the increased serum shift of these compounds, the representative 1e was highly potent

MK-0752
A4006-10 10 mg
EUR 316
Description: MK-0752 is a potent gamma secretase inhibitor in clinical development (IC50 ~50 nM).

MK-0752
A4006-100 100 mg
EUR 1302
Description: MK-0752 is a potent gamma secretase inhibitor in clinical development (IC50 ~50 nM).

MK-0752
A4006-5.1 10 mM (in 1mL DMSO)
EUR 305
Description: MK-0752 is a potent gamma secretase inhibitor in clinical development (IC50 ~50 nM).

MK-0752
A4006-50 50 mg
EUR 734
Description: MK-0752 is a potent gamma secretase inhibitor in clinical development (IC50 ~50 nM).

MK-0752
A4006-S Evaluation Sample
EUR 81
Description: MK-0752 is a potent gamma secretase inhibitor in clinical development (IC50 ~50 nM).

MK-2048
A4072-10 10 mg
EUR 351
Description: MK-2048 is a second generation inhibitor of HIV-1 integrase with IC50 values of 0.075 ?M and 0.08 ?M for subtype B and subtype C integrase, respectively.Integration of viral cDNA into the host genome is one of the definitive features of retrovirus replication.

MK-2048
A4072-100 100 mg
EUR 1186
Description: MK-2048 is a second generation inhibitor of HIV-1 integrase with IC50 values of 0.075 ?M and 0.08 ?M for subtype B and subtype C integrase, respectively.Integration of viral cDNA into the host genome is one of the definitive features of retrovirus replication.

MK-2048
A4072-5.1 10 mM (in 1mL DMSO)
EUR 456
Description: MK-2048 is a second generation inhibitor of HIV-1 integrase with IC50 values of 0.075 ?M and 0.08 ?M for subtype B and subtype C integrase, respectively.Integration of viral cDNA into the host genome is one of the definitive features of retrovirus replication.

MK-2048
A4072-50 50 mg
EUR 838
Description: MK-2048 is a second generation inhibitor of HIV-1 integrase with IC50 values of 0.075 ?M and 0.08 ?M for subtype B and subtype C integrase, respectively.Integration of viral cDNA into the host genome is one of the definitive features of retrovirus replication.

MK-8245
A4345-10 10 mg
EUR 350
Description: MK-8245 is a potent and liver-selective inhibitor of stearoyl-CoA desaturase (SCD) with IC50 value of 1nM [1].SCD1 represents a therapeutic target for the treatment of type II diabetes, dyslipidemia, obesity, and metabolic diseases.

MK-8245
A4345-200 200 mg
EUR 2055
Description: MK-8245 is a potent and liver-selective inhibitor of stearoyl-CoA desaturase (SCD) with IC50 value of 1nM [1].SCD1 represents a therapeutic target for the treatment of type II diabetes, dyslipidemia, obesity, and metabolic diseases.

MK-5 with vented cover (polycarbonate